Search results for "gene-expression profile"

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Peripheral T-cell lymphoma classification: the matter of cellular derivation.

2011

Peripheral T-cell lymphomas (PTCLs) represent approximately 12% of all non-Hodgkin's lymphomas in Western countries. They are quite heterogeneous as far as morphology and phenotype are concerned. Furthermore, until now, PTCLs could not be referred to specific normal counterparts, in contrast to B-cell-derived non-Hodgkin's lymphomas. In particular, in the last edition of the WHO classification of Tumors of the Hematopoietic and Lymphoid Tissues, for the majority of nodal PTCLs (including the not otherwise specified type and anaplastic large-cell lymphoma), the postulated cell of origin remained undefined. However, in the last few years, high-throughput genomic techniques, especially gene-ex…

T cellGene Expression ProfilingNot Otherwise SpecifiedT lymphocytesLymphoma T-Cell PeripheralTfhHematologyBiologymedicine.diseasePhenotypePeripheral T-cell lymphomaLymphomaGene expression profilingcytotoxicgene-expression profilemedicine.anatomical_structureImmunologymedicineCancer researchCytotoxic T cellHumansProspective Studiesperipheral T-cell lymphomaTumors of the hematopoietic and lymphoid tissuesExpert review of hematology
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